Human Nuclear Pore Complex

This behemoth, called the nuclear pore complex, controls the flow of molecules in and out of the nucleus of the cell, where the genome sits. Hundreds of these complexes exist in every cell. Each is made up of more than 1,000 proteins that together form rings around a hole through the nuclear membrane. nature expand

Last July, London-based firm DeepMind made public an artificial intelligence tool called AlphaFold. The software could predict the 3D shape of proteins from their genetic sequence with, for the most part, pinpoint accuracy. This transformed work on the pore complex and the studies of thousands of other biologists. expand